Thank you for your question. We can ensure that you eating durian and drinking Coca-Cola at the same time do no harm to your health. Related Items FAQ More on Journey Coca-Cola FAQs: Health What happens one hour after drinking a can of Coke?/ What happened after drinking Coca-Cola? Coca-Cola FAQs: Ingredients Will a tooth dissolve if it is left in Coca-Cola overnight? When did Coca-Cola first arrive in Singapore?